Blood Test Aims to Detect Parkinson’s in Early Stages

Researchers receive developed a blood test that they declare could help neurologists detect Parkinson’s disease and track the illness as it progresses.

“If felicitous, we expect our findings will change into another form into a valuable diagnostic tool conducive to Parkinson’s disease,” said study co-maker Judith Potashkin, professor of cellular and corpuscular pharmacology at Chicago Medical School, Rosalind Franklin University of Medicine and Science.

An estimated 60,000 canaille in the United States are diagnosed with Parkinson’s disease each year, according to the Parkinson’s Disease Foundation. There is none cure for the disease, which be possible to cause tremors and severely hamper motion. While medications can be helpful, the sickness gets worse over time, and medications observe not stop its progression.

Physicians traditionally diagnosed Parkinson’s by analyzing symptoms. Now, brain scans are suitable that provide insight, but scan images be possible to still leave room for doubt, Potashkin related.

In their new study, researchers maxim they’ve found two genetic markers that are 90 percent forcible at indicating the presence of Parkinson’s ail. The markers are related to in what manner the body processes glucose (blood sugar) and insulin, said study lead originator Jose Santiago, a research associate at Chicago Medical School.

The researchers in that case tracked 101 people with Parkinson’s and 91 well people. They found that gene “expression” changed significantly across three years in the Parkinson’s patients.

More inquiry is needed to confirm that the ground of admission works, and the researchers would like to ~ up it more accurate. Also, it’s not luminous how much the test might at last cost.

One goal is to “greatly” improve the precision of Parkinson’s diagnosis through a coalition of analysis of symptoms, brain scans and temper tests, Potashkin said. It would likewise help to diagnose Parkinson’s in seasonable stages and use blood tests to repression its progress and see if drugs drudge early on, she said.

A family test to diagnose Parkinson’s would conceivably exist “much less expensive and again easily accessible” than brain scans, afore~ Julie Andersen, a professor at Buck Institute during the term of Research on Aging in Novato, Calif.

Dr. Somshuvra Mukhopadhyay, some assistant professor of pharmaceutics at the University of Texas at Austin, called the fresh study “exciting.” However, he cautioned that “more distant work is necessary before this becomes a characteristic and clinical standard.”

It’s not unmixed whether Parkinson’s causes changes in the genes or whether the genes actually contribute to the development of Parkinson’s, the researchers before-mentioned. Both genes are associated with diabetes, and scientists mistrust there may be a link betwixt the two diseases.

“There has been a intimation from earlier clinical studies that diabetes may exist a risk factor for subsequent Parkinson’s exhibition,” Andersen said. “It is likewise possible that Parkinson’s and diabetes part similar underlying causes associated with aging.”

Source: U.S. Department of Health and Human Services

Filed in a state of inferiority to: Health, News and Articles Tagged: | Brain, Parkinsons

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