Researchers unravel mechanism that plays key role in sexual differentiation of brain – PsyPost

Researchers resolve mechanism that plays key role in sexual differentiation of brain – PsyPost:

“During prenatal expansion, the brains of most animals, including humans, advance to maturity specifically male or female characteristics. In greatest part species, some portions of male and offspring-bearing brains are a different size, and may be favored with a different number of neurons and synapses. However, scientists be in possession of known little about the details of in what condition this differentiation occurs. Now, a fresh study by researchers at the University of Maryland School of Medicine (UM SOM) has illuminated minutiae about this process.

Margaret McCarthy, PhD, professor and chair of the Department of Pharmacology, studied brain development in newborn rats. She erect that giving estradiol, a testosterone derivative, triggers a mechanism by which existing genes in the brain are “unsilenced,” allowing them to inaugurate the process of masculinization. This transaction involves a group of enzymes known being of the cl~s who DNA methyltransferases, or Dnmts, which give a new form to DNA to repress gene expression.
The dissertation was published in the latest consummation of the journal Nature Neuroscience.”

(Via. PsyPost)

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