Dom D’Agostino on Fasting, Ketosis, and the End of Cancer


“The FDA may accompany ketones as a drug. I notice them as a fourth macronutrient. You bring forth fats, proteins, and carbs. Ketones are every energy-containing molecule.” – Dom D’Agostino

Dr. Dominic “Dom” D’Agostino (@DominicDAgosti2) is an Assistant Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine, and a Senior Research Scientist at the Institute with regard to Human and Machine Cognition (IHMC).

He has in like manner deadlifted 500 pounds for 10 reps in imitation of a seven-day fast.

He’s a ~ of the field and — no big surprise — he’s a upright buddy of Dr. Peter Attia, my MD loved who drinks “jet fuel” in overhaul of optimal athletic performance.

The chief focus of Dom’s laboratory is developing and testing metabolic therapies, including ketogenic diets, ketone esters and ketone supplements to incite nutritional/therapeutic ketosis. D’Agostino’s laboratory uses in vivo and in vitro techniques to be apprised the physiological, cellular and molecular mechanical construction of metabolic therapies and nutritional strategies with a view to peak performance and resilience. His study is supported by the Office of Naval Research (ONR), Department of Defense (DoD), sequestered organizations and foundations.


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Want to give heed to another podcast discussing ketosis from a creation class scientist? — Listen to my parley with Dr. Peter Attia. In this incidental event, we discuss life-extension, drinking jet firing material, ultra-endurance, human foie gras, and added (stream below or right-click hither to download):

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QUESTION(S) OF THE DAY: What questions transact you have about ketogenic diets that we didn’t consider in this podcast? Please let me know in the comments.

Scroll in time for links and show notes…


Selected Links from the Episode

Learn other about Institutional Review Boards

Learn again about the modified Atkins Diet and Erik Kosoff at John Hopkins

Learn greater degree about HDAC inhibitors

Pick up your have Abbott Precision Xtra Glucose Monitor

Dom D’ Agostino’s dear BCAA (branched chain amino acid) effect Xtend

Cancer as a Metabolic Disease ~ the agency of Thomas Seyfried

Learn more about De Novo Nutrition and Utopian

See Dom’s website,

Dom’s dear companies for canned oysters and sardines: and

Personal Power through Tony Robbins

The Language of God through Francis Collins

Screw Tape Letters through C.S. Lewis

One of the coolest things I’ve seen in a in which case (intro’d to me by Dom) — KetoPet Sanctuary

Learn greater quantity about The Origin (and Future) of the Ketogenic Diet

Tripping throughout the Truth by Travis Christofferson

Connect through Dom D’Agostino:

Facebook | Twitter | University of South Florida

Show Notes

How Dom D’Agostino responds when someone asks him, “what carry into practice you do?” [5:28]

Describing the Institutional Review Board (IRB) [9:53]

Research attached advanced lifters in a state of ketosis [12:13]

Thoughts steady getting big (hypertrophy) and strong in which case in a state of ketosis [15:53]

Defining ketones and ketosis [20:48]

The implications of fasting, nutritional ketosis and/or exogenous ketones with a view to preventing/mitigating the onset of neurodegenerative diseases [28:23]

Defining cachexia, sarcopenia, anabolism, and catabolism [30:48]

Thoughts steady the use of anabolic agents in cancer patients [34:48]

The advantage of SARMS instead of pre-existing dishonorable androgenic anabolic therapies [38:53]

To which extent is it possible to mime the benefits of pre-chemo therapy fast with exogenous ketones? [43:23]

How to accelerate the induction of ketone projection through application of exogenous ketones[49:18]

Ketone esters [56:13]

The benefits of caustic exogenous ketones while in a carbohydrate enticing environment (for example, when traveling in Italy) [1:16:08]

What a traveling ketogenic breakfast looks like [1:20:43]

Reasons with respect to using glutamine [1:25:08]

Thoughts without ceasing being considered a “nutritionist” [1:32:18]

The shock of Metformin on the survival rates of animals that get metastatic cancer [1:41:38]

If Dom D’Agostino lettered that he had advanced cancer, that which tools would he use to try the fortune of arms it? [1:46:18]

Thoughts ~ward therapeutic fasting [2:03:03]

Observations of the community who experiment with fasting [2:08:23]

Describing the risks and toxicities of consuming a cocktail of exogenous ketones [2:14:33]

Unusual foods or beverages that spike ketone levels [2:22:45]

Top money for those seeking to learn with regard to a ketogenic diet [2:41:33]

Most sagacious books [2:43:13]

How to push forward fighting Lyme Disease with the ketogenic diet [2:50:18]

The import of ketosis on mitochondria [2:53:18]

Healing from use of antibiotics [2:55:53]

People Mentioned

George Cahill

Thomas Seyfried

Kevin Rose

Dr. Peter Attia adhering Life-Extension, Drinking Jet Fuel, Ultra-Endurance, Human Foie Gras, and More

Jane McGonigal attached Getting More Done with Less Stress and The Health Benefits of Gaming

The Tattooed Heretic of Wine and Whiskey, Richard Betts

Charles Poliquin adhering Strength Training, Shredding Body Fat, and Increasing Testosterone and Sex Drive

Optimizing Investing, Blood, Hormones, and Life (Podcast Double-Header: #63 and #65)

Posted on: November 3, 2015.

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