Mitochondrial Function: The Other Half Of The Anti-Aging Story

Telomere knowledge changed everything we knew about aging. But today, I poverty to talk to you about the other moiety of the anti-aging equation.

Regular readers determination already know by protecting your telomeres, you can slow — and even reverse — the aging series of measures.


You see, your telomeres are like feeble countdown clocks that protect the DNA in your cells. They diminish with each cell division. And the shorter they generate the faster you develop the signs of aging. So ~ means of protecting and nourishing them, you have power to literally turn back the years.

I was single in kind of the first doctors to deposit telomere science to the test. And conducive to years, I’ve been helping patients gauge, protect and lengthen their telomeres.

But I’ve too discovered that telomeres are only HALF the record when it comes to aging. Let me explain…

Telomeres countenance the DNA inside the nucleus of each cell in your body. But in that place is other DNA in each of your cells external the nucleus.

You see, your cells in addition contain tiny organelles called mitochondria. These are the fleet plants that turn fuel into spirit. And your mitochondria have their acknowledge DNA and their own impact ~ward the aging process.


Mainstream medicine ~y ignores the anti-aging power of mitochondria. But in today’s letter, I’m going to show you by what mode to boost mitochondria while at home.

But leading, let’s look at why your mitochondria are in like manner important…

Each of your cells has at minutest one of these tiny power plants. The mean proportion cell has 200. And cells because of important organs, like your heart and brain, can have more than 10,000.

But here’s the puzzle: As you age, these tiny control plants become damaged and start to die right side. And you lose your capacity to raise energy.

The first thing that happens is that your favose energy takes a dive. You feel tired and fatigued. But then they malfunction, and devastating diseases have power to follow:

Schizophrenia and bipolar disease;

Alzheimer’s and Parkinson’s distemper;

Epilepsy, migraines, and nerve pain;

Loss of muscle rule and balance;

Heart disease and strokes;




Hepatitis C and cirrhosis. 1

Today, this happens at a faster estimate than what your parents and grandparents able because now we’re living in a in a high degree. toxic environment. And exposure to toxic chemicals be possible to cause the body to age faster.

You observe, today, we’re faced with “accelerated aging” on this account that of environmental factors, such as cigarette sooty vapor and ultraviolet rays from the sunshine. And its effect can age you too soon.

But there are ways to attend mitochondria…

Here at the Sears Institute in quest of Anti-Aging Medicine, I help my patients debar and repair damage to the mitochondria.

And I cheat this not with Big Pharma meds, but with nutrients. Here are just four of the nutrients I approve that have been proven to abet your mitochondrial function and boost power.

CoQ10: Co-enzyme Q10 sparks your aging small room engines to make more energy. And it’s a mighty free radical scavenger, soaking up oxidized molecules under the jurisdiction they cause damage.


I recommend apprehension 50 mg of CoQ10 daily. Look towards the ubiquinol form. It’s greater quantity powerful and much easier for your body to absorb.

Acetyl-L-Carnitine: The amino sour L-carnitine plays a critical role in composition energy in your cells. It transports adipose acids into the mitochondria. There they have power to be burned for fuel. It also carries toxic waste out before it can do damage.

But as you years of discretion, carnitine levels in your tissues ear-ring.2 That’s why you want acetyl-L-carnitine (ALC). Your material substance converts L-carnitine to ALC. And studies usher when your mitochondria slow down, ALC be possible to fire them up again.3 Studies besides show ALC reverses the malfunction in mitochondria in the same proportion that you age. ALC can also improve brain exploit and increase neurotransmitters.4


The most excellent source of L-carnitine is grass-fed red viands. But you can also supplement. I insinuate taking at least 500 mg of ALC each day on an empty stomach. Look during the term of a formula with only L-carnitine and not D, L-carnitine. D-carnitine is synthetic.

N-Acetyl-Cysteine (NAC): This amino tart is also a powerful antioxidant. You care for, NAC helps make glutathione, the body’s ~ly powerful antioxidant. Glutathione is the the bulk line of defense for mitochondria. It helps prevent and repair oxidative damage, thus protecting your mitochondria.6,7

And there’s not the same reason I recommend NAC to my patients. Studies color it protects your telomeres from oxidative mar.8 So it throws a the same-two anti-aging punch. I inform supplementing with 500 mg per generation.

Rhodiola Rosea: This tough, little golden flower is native to the septentrion mountains of Eastern Siberia. And I’ve seen its susceptibility to energize my patients. In honest a few months, they are visibly junior and stronger. And they tell me they be stirred that way, too.

Research proves which I’ve seen in my patients. Lab Rats given rhodiola were ingenious to swim 25% longer before right exhausted.9 That’s because the herb helped trigger pluck synthesis in the mitochondria.

Rhodiola can also energize people. Just one 200 mg draught helped people in one study improve their test endurance.10 In another study, students infectious 100 mg of rhodiola every lifetime improved their capacity to work. Their acquired knowledge ability increased by 61% and their tire levels dropped by 30%.11


You be possible to find Rhodiola tea in your local health food store. Or you be possible to take it in capsule form. It’s in like manner called golden root or roseroot. But represent sure you get a formula through enough of the herb’s quick compounds. Look for an extract standardized to hold at least 3% rosavins and 1% salidroside. That’s the same ratio found in the natural take ~.

I recommend taking 200 mg a set time on an empty stomach, preferably in the daybreak because rhodiola stimulates your brain.

I’ve been tinkering with a new formula to support your mitochondria. And it contains every part of the ALC, NAC, and rhodiola you be in want of. So stay tuned.

To Your Good Health,


Al Sears, MD, CNS

1Neustadt J, Pieczenik SR. “Medication-induced mitochondrial impair and disease.” Mol Nutr Food Res. 2008;52(7):780-8.
2Opalka, J., Gellerich, F., Zierz, S. “Age and sex dependency of carnitine concentrations in human serum and skeletal muscle.” Clinical Chemistry, 2001, 47: 12, 2150-2153.
3Kidd PM. “Neurodegeneration from mitochondrial dearth: nutrients, stem cells, growth factors, and prospects during the term of brain rebuilding using integrative management.” Altern Med Rev. 2005; 10(4):268-93.
4Hagen, TM., Wehr, CM., Ames, BN. “Mitochondrial deterioration in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone.” Ann N Y Acad Sci, 1998;854:214-23.
5Arakawa M, Ito Y. “N-acetylcysteine and neurodegenerative diseases: basic and clinical pharmacology.” Cerebellum. 2007;6(4):308-14.
6Montserrat Marí, Albert Morales, Anna Colell et al. “Mitochondrial Glutathione, a Key Survival Antioxidant.” Antioxid Redox Signal. 2009; 11(11): 2685–2700.
7Kelly GS “Clinical applications of N-acetylcysteine.” Altern Med Rev. 1998;3(2):114-27.
8Ludlow A, Spangenburg E, Chin E, Cheng W, Roth S. “Telomeres Shorten in Response to Oxidative Stress in Mouse Skeletal Muscle Fibers.” J Gerontol A Biol Sci Med Sci. 2014;69(7):821-30.
9Abidov M, Crendal F, Grachev S, et al. “Effect of extracts from Rhodiola rosea and Rhodiola crenulata (Crassulaceae) roots on ATP content in mitochondria of skeletal muscles.” Bull Exp Biol Med. 2003;136(6):585-7.
10De Bock K, Eijnde BO, Ramaekers M, Hespel P. “Acute Rhodiola rosea intake be able to improve endurance exercise performance.” Int J Sport Nutr Exerc Metab. 2004;14(3):298-307.
11Spasov AA et al. “A double-labyrinthine, placebo-controlled pilot study of the stimulating and adaptogenic validity of Rhodiola rosea SHR-5 select on the fatigue of students caused ~ the agency of stress during an examination period by a repeated low-dose regimen.” Phytomedicine. 2000;7(2):85-9.

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