Using oxygen to sterilise medical implants could save time and money

Rediguieri, C.F. et al. University of Bath. Published online: April 2016

International researchers led ~ means of the University of Bath have demonstrated a inferior, effective and environmentally-friendly way to sterilise therapeutic implants without changing their properties, in stand out in opposition to some techniques.

This inexpensive technology could catch time and money while effectively sterilising therapeutic implants, does not require extensive breeding and produces no waste products

Scientists from the University of Bath’s Department of Pharmacy & Pharmacology and Centre against Regenerative Medicine and from the Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil, showed that ozone gas, obtained by passing electricity through oxygen, effectively sterilises any of the most common types of polymer used in therapeutical implants.

Polymer implants, such as screws, pins and stents, are commonly used in surgical treatments, and in that place is an increasing use of implantable polymers in fields of the like kind as drug delivery, regenerative medicine and texture engineering.

These materials must be sterile before use, but some methods of sterilisation become different their physical or chemical properties, potentially reducing achievement.

The researchers showed that exposing the implants to of the same kind with few as two controlled ‘pulses’ of ozone elastic fluid could sterilise the polymer, called poly(lactic-co-glycolic sharp) (PLGA), killing spores of the Geobacillus stearothermophilus bacteria, the most common biological indicator used for validation of sterilisation processes.

Ozone management caused no changes in the PLGA and none loss of function, with cells uniformly able to grow on the polymer stage, as they would in treatments.

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