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Tyme Technologies Announces Launch of a Pancreatic Research Program with the Mayo Clinic Led by Dr. Martin Fernandez-Zapico

NEW YORK, Dec. 13, 2016, TYMI, (GLOBE NEWSWIRE) — Tyme Technologies, Inc. (“Tyme” or “the Company”) (OTCQB:TYMI), a clinical-theatre pharmaceutical company focused on developing very much targeted cancer therapeutics for a uncontracted range of oncology indications, today announced the hurl of a Pancreatic Research Program with the Mayo Clinic led by Dr. Martin Fernandez-Zapico.

Dr. Martin E. Fernandez-Zapico, Associate Professor of Medicine and Pharmacology at the Mayo Clinic, is one international expert in the field of pancreatic cancer, a malady predicted to be the second leading cause of cancer in 2030. Dr. Fernandez-Zapico’s programs are affiliated with the Mayo Clinic Cancer Center, Department of Oncology, Division of Gastroenterology and Hepatology, and the Center during Cell Signaling in Gastroenterology. His study is supported by the National Institutes of Health (NIH), the NIH-funded Mayo Clinic Pancreatic Cancer Specialized Program of Research Excellence (SPORE), the NIH-funded Mayo Clinic Center because of Cell Signaling in Gastroenterology, and the Leukemia and Lymphoma Foundation. His be has been seminal for the reason of mechanisms driving this malignancy and serves during the time that a foundation for multiple National Cancer Institute sponsored clinical trials.

“Tyme is extremely pleased to exist working with Dr. Fernandez-Zapico of the Mayo Clinic in every effort to potentially discover the coming time cure of pancreatic cancer. I rely upon the pancreatic research experiments planned through Dr. Fernandez-Zapico, using our see preprinter discoveries and supported by Tyme, could persuade to significant progress in battling this devastating con~ation of cancer. We look forward to continuing our clinical progression in a continuously ascending gradation program in pancreatic and other cancers, based up~ collaborations with Mayo and other most important institutions,” said Dr. Del Priore, Chief Medical Officer of Tyme.

About Tyme

Our inquiry and development efforts are based in successi~ patented technologies and our patent unsettled proprietary platform technology, for which we retain global IP and commercial rights. Our have the ~ of program is SM-88, a see preprinter combination drug product. We believe SM-88 is a foremost-in-class oncology therapy that increases the prerogative of the body’s innate defenses to make useful oxidative stress to kill cancer cells. SM-88 is designed to enter only living cancer cells without toxic goods and without involving healthy body accumulation. We believe that SM-88’s therapeutic potential is based on its facility to increase the availability of bountiful radicals and promote their entry into cancer cells through stripping the cancer cells of their ordinary barriers to these toxic electrons. SM-88 is a conspiracy of a proprietary novel molecule by three currently-marketed drugs that are in general considered safe for their already approved indications, what one. are in areas other than cancer treatment.

Forward-Looking Statements

In addition to historical advice, this press release contains forward-looking statements inside of the meaning of the U.S. Private Securities Litigation Reform Act of 1995, Section 27A of the U.S. Securities Act of 1933, and Section 21E of the U.S. Securities Exchange Act of 1934. Such brazen-faced-looking statements may include projections respecting Tyme’s future performance, and readers be possible to identify forward-looking statements by sentences or passages involving the employment of terms such as “anticipates,” “believes,” “designed,” “could,” “estimates,” “expects,” “intends,” “may,” “plans,” “possible,” “predicts,” “projects,” “should,” “would” and uniform expressions intended to identify forward-looking statements. The at the fore part-looking statements contained in this clasp release are based on management’s current expectations, that are subject to uncertainty, risks and changes in pecuniary standing that are difficult to predict and crowd of which are outside of Tyme’s mastery. Forward-looking statements within this crowd release include, without limitation, statements respecting our drug development strategies, the curative mechanisms of our drug candidates and our completed and planned clinical trials. These statements imply known and unknown risks, uncertainties and other factors that may cause the Company’s actual results, acting or achievements to be materially different from any historical results and time to come results, performances or achievements expressed or implied through the forward-looking statements. These risks and uncertainties hold, but are not limited to, the factors described in the part captioned “Risk Factors” of Tyme’s Annual Report steady Form 10-K filed with the U.S. Securities and Exchange Commission on March 30, 2016 (available at www.sec.gov).

Contact:

Lisa Wilson
In-Site Communications, Inc.
T: (212) 452-2793
E: lwilson@insitecony.com

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THANKS!

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Want Real Information About Psychiatric Drugs? Visit CrazyMeds

Welcome to Crazymeds, to which place you can learn what’s agreeable, what’s bad, what’s engaging, and what’s plain weird and farcical about the medications used to gratification depression, bipolar disorder, schizophrenia, epilepsy, migraines, vexation, neuropathic pain, or whatever psychiatric and/or neurological estate you might have. The information forward this site is to help you be with your doctor(s) to discover the right treatment options. Too great number of us get nothing more than 15-note appointments with overworked doctors or manage-practitioners, so we need all the succor we can get. We need to deliberate to our prescribers about the most profitably medication1 to treat our conditions, and not the greatest number profitable ones, or the cheapest ones2.

OK, in immobility “best” usually translates to “minutest bad.” If you know the nominate of the medication(s) you’re looking in spite of, you’ll probably want our limit of drugs by names and rank/category. There’s also our plenteous larger list of all the meds we apprehend about to treat various conditions, including whole the brand/trade names we can find for every med in every country in which each is to be turned to account. We also have the drugs sorted into vulgar categories with lots of overlapping memberships:

Antidepressants, like Celexa and Effexor, with respect to the treatment of depression (duh), uneasiness, and other conditions.

Mood Stabilizers, so as Lamictal and Seroquel, for the handling of bipolar disorder3.

Antiepileptic drugs (AEDs), in addition known as anticonvulsants, which are used to handle one or more of epilepsy, bipolar ailment, and migraines. Depakote and Stavzor exactly have FDA approval to treat the whole of three.

Antipsychotics, such as Invega and Abilify, to deal with schizophrenia, bipolar, and depression.

Anxiolytics – in English: drugs to banquet anxiety and the alphabet soup of perplexity spectrum disorders like GAD, PTSD and OCD. These are mostly SSRIs like Lexapro, benzodiazepines, and a scarcely any specifically non-benzodiazepine anxiolytic drugs like BuSpar.

Benzodiazepines like Valium (diazepam) and Xanax (alprazolam), which are used to treat anxiety, epilepsy, sleep disorders and more.

Medications during the term of Headaches and Neuropathic Pain, which are in the first place AEDs like Topamax and Neurontin, and more antidepressants, like Cymbalta. “Headache” usually, nevertheless does not always mean “migraine.” Like every condition discussed on this site, officially or unofficially, headaches are a representation disorder. Neuropathic pain is a gripe-all term for specific conditions such as trigeminal neuralgia (sometimes misdiagnosed during the time that migraines) to “chronic idiopathic pain” – that is doctorese for, “it may or may not exist psychological in origin, but the punishment is obviously real even if we don’t require a clue as to what’s causing it.”

Medications in spite of Adult ADD/ADHD. Mostly stimulants like Adderall, however also non-stimulant medications like Strattera.

Medications since Sleep Disorders include stimulants, benzodiazepines, and non-benzodiazepine hypnotics like Ambien.

Stimulants, of the like kind as Adderall and Provigil (modafinil), to delight adult ADD/ADHD, sleep disorders like narcolepsy, and other terms.

Crazymeds is the site for the obsessed and depressed, the manic and the panicked, the schizophrenic and epileptic, the migraineurs and bipolar, those through GAD, SAD, OCD, PTSD, in disquiet or have an otherwise non-gauge brain4. If you have any precise questions about a drug that wasn’t answered on its page, couldn’t find the put ~s into you’re interested in, or wish some help in figuring out which medication is the right one instead of you, then visit Crazy Talk: Our court of justice for the mentally interesting. We aren’t doctors or anything, and we don’t diagnose, no more than we have more experience than we at any time wanted when it comes to brain cooties and the crazy meds used to discourse them. We’re all about helping harvested land other know what the drugs can and cannot do, what they are in a fair way to do for us and to us, and be with our doctors to make the most of all, or least bad, choice in medication(s) taken in the character of quickly as possible.

For real, CrazyMeds is unit of the most helpful plain-english information sites regarding psychiatric / neurological drugs and the kind of exactly they DO to your brain. If you’ve ~more felt like a human lab experiment just being handed one prescription from another, CrazyMeds can help you be an intelligent being what effects the drugs have and in what manner they work. The site also discusses realistic take ~seffects such as the ever-attentive “head zaps” of SSRIs and others that doctors solemnize saying we make up for attention.

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Help With Pharmacology

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Significant ranking boost for Monash Pharmacy

OzTREKK represents the most judicious in Australian education.

Monash University has welcomed the latest Academic Ranking of World Universities (ARWU) let out, which ranks Monash’s Clinical Medicine and Pharmacy because 34th in the world and second in Australia. This is up from an estimated rank of 76th in the terraqueous globe and third in Australia in 2015.

Monash Pharmacy gets significant ranking boost

Study at Monash University—the number 1 pharmacy exercise in Australia!

This result follows Monash’s inclusion up~ the Reuters international rankings as Australia’s back most innovative university across Asia. It in like manner follows Monash moving from an estimated be ~ed of 114th to 79th globally in the overall Academic Ranking of World Universities in August, and actuality ranked 4th in the world because Pharmacy and Pharmacology in the 2016 QS World University rankings ~ dint of. Subject.

Monash continues to be ranked in the rise above 200 in all five of the ARWU province rankings, including Natural Sciences and Mathematics (ranked other in Australia); Engineering/Technology and Computer Sciences; Life and Agriculture Sciences; Clinical Medicine and Pharmacy; and Social Sciences.

Professor Christina Mitchell, Academic Vice-President and Dean, Medicine Nursing and Health Sciences said it was an outstanding result during staff and students.

“Medicine and Pharmacy it being so that rank second in Australia and 34th in the globe, representing an increase of 42 places. This peculiar result highlights our commitment to between nations collaboration and research excellence. Importantly, the ranking demonstrates the contributions, reference to a committee and quality of our staff.”

Professor Bill Charman, Dean of the Faculty of Pharmacy and Pharmaceutical Sciences, uttered “This significant improvement reflects the extent of room of our life science and pharmaceutical researchers to undertake profound quality basic research, as well in the same proportion that pursuing translational opportunities in partnership through industry and government in an increasingly snappish-disciplinary manner. Such outcomes have besides been reflected in the increasing equal in ~ of our staff recognised as Highly Cited Researchers.”

ARWU has been presenting the creation top 500 universities annually since 2003, based up~ the body a set of objective indicators and third part-party data.

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THC Makes Cannabis Ideal for Treating Asthma, Study Shows

cannabis-asthmaAnna Hunt, Staff
Waking Times

A unused clinical study reports that cannabis acts like a bronchodilator, meaning that it dilates the bronchi and bronchioles, increasing airflow to the lungs. This associate-reviewed study was published in the Journal of Pharmacology and Experimental Therapeutics. It claims that cannabinoids shield the lungs from constriction and be able to be quite helpful for asthma patients.

The study compared the personal estate of six cannabinoids – THC, CBD, CBG, CBC, CBD-A, and THC-V – adhering contractions of the guinea pig-isolated trachea and bronchoconstriction induced by resolution stimulation in anesthetized guinea pigs. A team of researchers at the King’s College London, led ~ dint of. Raj Makwana, discovered the following:

Only Δ(9)-tetrahydrocannabinol [THC] inhibited TNF-α-enhanced vagal-induced bronchoconstriction, neutrophil recruitment to the airways, and citric acid-induced cough responses.

Tetrahydrocannabivarin [THC-V] imperfectly inhibited the TNF-α-enhanced hardihood-evoked contractions, whereas the other cannabinoids were free from effect. (Source)

This is great word for those with asthma, who frequently suffer from bronchoconstriction, the constriction of the airways in the lungs, nose and ~piece due to the tightening of surrounding muscles. Because of this, an asthma attack limits a person’s oxygen intake. Low-on a ~ inflammation can also be found in bronchi and bronchioles of asthma sufferers.

Over the after all the rest few decades, we’ve come to preferable understand the role of cannabinoids ~ward the human body. Cannabinoid receptors are grant throughout the body. This explains why people can benefit from cannabis in in this way many different ways.

Cannabinoid receptors be in actual possession of been found in human lung texture, although in relatively low concentrations, and are opinion to play a vital role in the order of inflammation, muscular contractions and dilations, and uncertain metabolic processes. ~ Pulmonary Pathology (Source)

Other studies take shown that cannabis has little to none long-term effect on the lungs. For example, researchers out of the University of California, San Francisco, institute:

Occasional and low cumulative marijuana conversion to an act was not associated with adverse goods on pulmonary function. (Source)

Even for the re~on that early as in 1973, scientists were discovering the bronchodilatory purport of cannabis smoke. A study conducted ~ dint of. Louis Vachon, M.D. et al at Boston University was the elementary to state:

Marijuana smoke, unlike cigarette fumigate, causes bronchodilatation rather than bronchoconstriction and, heterogeneous opiates, does not cause central respiratory blues. (Source)

In addition to air path constriction, people experiencing an asthma charge also suffer from significant pain. Numerous studies be favored with shown that cannabis has powerful annoy-reducing properties. The positive impact forward the respiratory system cannot be denied.

It’s not remarkable that anyone with asthma or respiratory issues would be anxious about smoking cannabis, but physicians in states at what place medical cannabis is legal are starting to decree it to patients for treating asthma.

Dr. Dustin Sulak, a chief medical cannabis physician, finds that vaporizing cannabis is a highly effective solution for asthma patients. This is as a good vaporizer provides superior degree of heat control.

“Probably 90% of rabble with asthma can take a uncompounded vaporize inhalation,” Dr. Sulak states.

“If they bring about it right, they’re going to be able to breathe deeper, expand their lungs, and relieve constriction.”

Dr. Sulak recommends a diurnal dosing to get a baseline proportion of medication in your system toward better overall asthma control. (Source)

Please allotment with us any of your experiences in treating asthma with cannabis.

About the Author

Anna Hunt is co-owner of OffgridOutpost.com, an online store sacrifice GMO-free healthy storable food and pinch kits. She is also the stick writer for WakingTimes.com. Anna is a certified Hatha yoga teacher and founder of Atenas Yoga Center. She enjoys raising her children and core a voice for optimal human soundness and wellness. Visit her essential oils abundance here. Visit Offgrid Outpost on Facebook.

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